timing of breast cancer surgery

For premenopausal women, the effect of timing of surgery in relation to the menstrual cycle is unclear. Evidence suggests that the timing of surgical resection may be relevant to outcome, with a possible advantage to the early luteal phase (approximately days 14 to 20 of the menstrual cycle).83,84 However, this association is inconsistent, and available data are inadequate to provide a recommendation about timing of surgery.