differences of Chemotherapy and endocrine therapy in breast cancer

However, it is important to note that the merits of chemotherapy compared with endocrine therapy for younger women are still being assessed. Trials to date have compared chemotherapy alone with endocrine therapy alone. Trials should now be designed to compare chemotherapy followed by tamoxifen with endocrine therapy alone. The current standard of care for women with hormone receptor positive tumours is treatment with both chemotherapy and endocrine therapy; however, some younger women with very good prognosis may decide to have endocrine therapy alone. Trials to determine the impact on disease outcome of chemotherapy plus endocrine therapy are continuing.